Which Antidepressants Are Most Likely to Cause Weight Gain
Some antidepressants are more commonly associated with weight gain than others. These include certain tricyclic antidepressants, mirtazapine, paroxetine, and some older selective serotonin reuptake inhibitors. They may increase appetite or affect how the body stores fat.
Why Antidepressants Can Lead to Weight Gain
Weight gain can occur because of increased appetite, cravings for carbohydrates, or changes in metabolism. Some medications may also cause fatigue that reduces physical activity. Individual responses vary, and not everyone taking these drugs will gain weight.
Managing Weight While Taking Antidepressants
Regular exercise, balanced meals, and portion control can help limit weight gain. Talking with a doctor before stopping or changing medication is important. A clinician may adjust the dose, switch medications, or add a treatment plan to support weight management.
For more information on medication side effects, visit the National Institutes of Health.
