What Is the Fungal Infection in The Last of Us
The Last of Us depicts a global pandemic caused by a mutated Cordyceps fungus. The fungus infects humans, takes control of their behavior, and eventually kills them. It spreads primarily through bites and spores.
Real-World Fungi Related to Cordyceps
Real Cordyceps species typically infect insects, not humans. Ophiocordyceps unilateralis manipulates ant behavior, a phenomenon sometimes called "zombie ant" syndrome. Human infection by Cordyceps is extremely rare and usually occurs only in immunocompromised individuals.
Could a Cordyceps-Like Human Pandemic Happen
Most fungi cannot survive at human body temperature. Rising global temperatures and fungal adaptation are areas of ongoing research. Scientists study fungal pathogens to understand potential future threats, noting that while a Cordyceps pandemic remains unlikely, emerging fungal diseases are a real public health concern. Learn more about fungal diseases from the CDC.
